The antitumor activity of human Vγ9Vδ2 T cells is impaired by TGF-β through significant phenotype, transcriptomic and metabolic changes

Despite significant advances, the eradication of cancer remains a clinical challenge which justifies the urgent exploration of additional therapeutic strategies such as immunotherapies. Human peripheral Vγ9Vδ2 T cells represent an attractive candidate subset for designing safe, feasible and effectiv...

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Detalles Bibliográficos
Autores principales: Rafia, Chirine, Loizeau, Clément, Renoult, Ophélie, Harly, Christelle, Pecqueur, Claire, Joalland, Noémie, Scotet, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893774/
https://www.ncbi.nlm.nih.gov/pubmed/36741364
http://dx.doi.org/10.3389/fimmu.2022.1066336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893774/
https://www.ncbi.nlm.nih.gov/pubmed/36741364
http://dx.doi.org/10.3389/fimmu.2022.1066336

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