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The antitumor activity of human Vγ9Vδ2 T cells is impaired by TGF-β through significant phenotype, transcriptomic and metabolic changes
Despite significant advances, the eradication of cancer remains a clinical challenge which justifies the urgent exploration of additional therapeutic strategies such as immunotherapies. Human peripheral Vγ9Vδ2 T cells represent an attractive candidate subset for designing safe, feasible and effectiv...
Autores principales: | Rafia, Chirine, Loizeau, Clément, Renoult, Ophélie, Harly, Christelle, Pecqueur, Claire, Joalland, Noémie, Scotet, Emmanuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893774/ https://www.ncbi.nlm.nih.gov/pubmed/36741364 http://dx.doi.org/10.3389/fimmu.2022.1066336 |
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