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Computational design of custom therapeutic cells to correct failing human cardiomyocytes

BACKGROUND: Myocardial delivery of non-excitable cells—namely human mesenchymal stem cells (hMSCs) and c-kit(+) cardiac interstitial cells (hCICs)—remains a promising approach for treating the failing heart. Recent empirical studies attempt to improve such therapies by genetically engineering cells...

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Detalles Bibliográficos
Autores principales: Tieu, Andrew, Phillips, Katherine G., Costa, Kevin D., Mayourian, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894098/
https://www.ncbi.nlm.nih.gov/pubmed/36743445
http://dx.doi.org/10.3389/fsysb.2023.1102467