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Computational design of custom therapeutic cells to correct failing human cardiomyocytes
BACKGROUND: Myocardial delivery of non-excitable cells—namely human mesenchymal stem cells (hMSCs) and c-kit(+) cardiac interstitial cells (hCICs)—remains a promising approach for treating the failing heart. Recent empirical studies attempt to improve such therapies by genetically engineering cells...
Autores principales: | Tieu, Andrew, Phillips, Katherine G., Costa, Kevin D., Mayourian, Joshua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894098/ https://www.ncbi.nlm.nih.gov/pubmed/36743445 http://dx.doi.org/10.3389/fsysb.2023.1102467 |
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