Human T cells recognize HLA-DP–bound peptides in two orientations

Human leukocyte antigen (HLA) molecules present small peptide antigens to T cells, thereby allowing them to recognize pathogen-infected and cancer cells. A central dogma over the last 50+ y is that peptide binding to HLA molecules is mediated by the docking of side chains of particular amino acids i...

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Detalles Bibliográficos
Autores principales: Klobuch, Sebastian, Lim, Jia Jia, van Balen, Peter, Kester, Michel G. D., de Klerk, Wendy, de Ru, Arnoud H., Pothast, Cilia R., Jedema, Inge, Drijfhout, Jan W., Rossjohn, Jamie, Reid, Hugh H., van Veelen, Peter A., Falkenburg, J. H. Frederik, Heemskerk, Mirjam H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894132/
https://www.ncbi.nlm.nih.gov/pubmed/36442096
http://dx.doi.org/10.1073/pnas.2214331119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894132/
https://www.ncbi.nlm.nih.gov/pubmed/36442096
http://dx.doi.org/10.1073/pnas.2214331119

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