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Acetyl-CoA-mediated autoacetylation of fatty acid synthase as a metabolic switch of de novo lipogenesis in Drosophila

De novo lipogenesis is a highly regulated metabolic process, which is known to be activated through transcriptional regulation of lipogenic genes, including fatty acid synthase (FASN). Unexpectedly, we find that the expression of FASN protein remains unchanged during Drosophila larval development fr...

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Detalles Bibliográficos
Autores principales: Miao, Ting, Kim, Jinoh, Kang, Ping, Fujiwara, Hideji, Hsu, Fong-Fu, Bai, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894184/
https://www.ncbi.nlm.nih.gov/pubmed/36459649
http://dx.doi.org/10.1073/pnas.2212220119