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Acetyl-CoA-mediated autoacetylation of fatty acid synthase as a metabolic switch of de novo lipogenesis in Drosophila
De novo lipogenesis is a highly regulated metabolic process, which is known to be activated through transcriptional regulation of lipogenic genes, including fatty acid synthase (FASN). Unexpectedly, we find that the expression of FASN protein remains unchanged during Drosophila larval development fr...
Autores principales: | Miao, Ting, Kim, Jinoh, Kang, Ping, Fujiwara, Hideji, Hsu, Fong-Fu, Bai, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894184/ https://www.ncbi.nlm.nih.gov/pubmed/36459649 http://dx.doi.org/10.1073/pnas.2212220119 |
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