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The kinase occupancy of T cell coreceptors reconsidered

The sensitivity of the αβ T cell receptor (TCR) is enhanced by the coreceptors CD4 and CD8αβ, which are expressed primarily by cells of the helper and cytotoxic T cell lineages, respectively. The coreceptors bind to major histocompatibility complex (MHC) molecules and associate intracellularly with...

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Detalles Bibliográficos
Autores principales: Mørch, Alexander M., Schneider, Falk, Jenkins, Edward, Santos, Ana Mafalda, Fraser, Scott E., Davis, Simon J., Dustin, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894195/
https://www.ncbi.nlm.nih.gov/pubmed/36454761
http://dx.doi.org/10.1073/pnas.2213538119