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Deletion of Jazf1 gene causes early growth retardation and insulin resistance in mice

Single-nucleotide polymorphisms in the human juxtaposed with another zinc finger protein 1 (JAZF1) gene have repeatedly been associated with both type 2 diabetes (T2D) and height in multiple genome-wide association studies (GWAS); however, the mechanism by which JAZF1 causes these traits is not yet...

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Detalles Bibliográficos
Autores principales: Lee, Hui-Young, Jang, Hye Rim, Li, Hui, Samuel, Varman T., Dudek, Karrie D., Osipovich, Anna B., Magnuson, Mark A., Sklar, Jeffrey, Shulman, Gerald I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894197/
https://www.ncbi.nlm.nih.gov/pubmed/36442127
http://dx.doi.org/10.1073/pnas.2213628119