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Comprehensive mapping of alternative polyadenylation site usage and its dynamics at single-cell resolution
Alternative polyadenylation (APA) plays an important role in posttranscriptional gene regulation such as transcript stability and translation efficiency. However, our knowledge about APA dynamics at the single-cell level is largely unexplored. Here, we developed single-cell polyadenylation sequencin...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894249/ https://www.ncbi.nlm.nih.gov/pubmed/36454750 http://dx.doi.org/10.1073/pnas.2113504119 |