Comprehensive mapping of alternative polyadenylation site usage and its dynamics at single-cell resolution

Alternative polyadenylation (APA) plays an important role in posttranscriptional gene regulation such as transcript stability and translation efficiency. However, our knowledge about APA dynamics at the single-cell level is largely unexplored. Here, we developed single-cell polyadenylation sequencin...

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Detalles Bibliográficos
Autores principales: Wang, Junliang, Chen, Wei, Yue, Wenjun, Hou, Wenhong, Rao, Feng, Zhong, Hanbing, Qi, Yuanming, Hong, Ni, Ni, Ting, Jin, Wenfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894249/
https://www.ncbi.nlm.nih.gov/pubmed/36454750
http://dx.doi.org/10.1073/pnas.2113504119

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