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Stimulation of soluble guanylate cyclase by vericiguat reduces skeletal muscle atrophy of mice following chemotherapy

Background: The chemotherapeutic doxorubicin (DOX) promotes severe skeletal muscle atrophy, which induces skeletal muscle weakness and fatigue. Soluble guanylate cyclase (sGC) contributes to a variety of pathophysiological processes, but whether it is involved in DOX-induced skeletal muscle atrophy...

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Detalles Bibliográficos
Autores principales: Hu, Bo-ang, Li, Yu-lin, Han, Hai-tao, Lu, Bin, Jia, Xu, Han, Lu, Ma, Wei-xuan, Zhu, Ping, Wang, Zhi-hao, Zhang, Wei, Zhong, Ming, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894251/
https://www.ncbi.nlm.nih.gov/pubmed/36744261
http://dx.doi.org/10.3389/fphar.2023.1112123