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Mechanism of actin filament branch formation by Arp2/3 complex revealed by a high-resolution cryo-EM structureof the branch junction

We reconstructed the structure of actin filament branch junctions formed by fission yeast Arp2/3 complex at 3.5 Å resolution from images collected by electron cryo-microscopy. During specimen preparation, all of the actin subunits and Arp3 hydrolyzed their bound adenosine triphosphate (ATP) and diss...

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Detalles Bibliográficos
Autores principales: Chou, Steven Z., Chatterjee, Moon, Pollard, Thomas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894260/
https://www.ncbi.nlm.nih.gov/pubmed/36442092
http://dx.doi.org/10.1073/pnas.2206722119