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A dynamic template complex mediates Munc18-chaperoned SNARE assembly

Munc18 chaperones assembly of three membrane-anchored soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) into a four-helix bundle to mediate membrane fusion between vesicles and plasma membranes, leading to neurotransmitter or insulin release, glucose transporter (GLUT4)...

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Detalles Bibliográficos
Autores principales: Yang, Jie, Jin, Huaizhou, Liu, Yihao, Guo, Yaya, Zhang, Yongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894263/
https://www.ncbi.nlm.nih.gov/pubmed/36454760
http://dx.doi.org/10.1073/pnas.2215124119