A cis-regulatory lexicon of DNA motif combinations mediating cell-type-specific gene regulation

Gene expression is controlled by transcription factors (TFs) that bind cognate DNA motif sequences in cis-regulatory elements (CREs). The combinations of DNA motifs acting within homeostasis and disease, however, are unclear. Gene expression, chromatin accessibility, TF footprinting, and H3K27ac-dep...

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Detalles Bibliográficos
Autores principales: Donohue, Laura K.H., Guo, Margaret G., Zhao, Yang, Jung, Namyoung, Bussat, Rose T., Kim, Daniel S., Neela, Poornima H., Kellman, Laura N., Garcia, Omar S., Meyers, Robin M., Altman, Russ B., Khavari, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894309/
https://www.ncbi.nlm.nih.gov/pubmed/36742369
http://dx.doi.org/10.1016/j.xgen.2022.100191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894309/
https://www.ncbi.nlm.nih.gov/pubmed/36742369
http://dx.doi.org/10.1016/j.xgen.2022.100191

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