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A cis-regulatory lexicon of DNA motif combinations mediating cell-type-specific gene regulation
Gene expression is controlled by transcription factors (TFs) that bind cognate DNA motif sequences in cis-regulatory elements (CREs). The combinations of DNA motifs acting within homeostasis and disease, however, are unclear. Gene expression, chromatin accessibility, TF footprinting, and H3K27ac-dep...
Autores principales: | Donohue, Laura K.H., Guo, Margaret G., Zhao, Yang, Jung, Namyoung, Bussat, Rose T., Kim, Daniel S., Neela, Poornima H., Kellman, Laura N., Garcia, Omar S., Meyers, Robin M., Altman, Russ B., Khavari, Paul A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894309/ https://www.ncbi.nlm.nih.gov/pubmed/36742369 http://dx.doi.org/10.1016/j.xgen.2022.100191 |
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