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Glutamine synthetase expression rescues human dendritic cell survival in a glutamine-deprived environment

INTRODUCTION: Glutamine deficiency is a well-known feature of the tumor environment. Here we analyzed the impact of glutamine deprivation on human myeloid cell survival and function. METHODS: Different types of myeloid cells were cultured in the absence or presence of glutamine and/or with L-methion...

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Detalles Bibliográficos
Autores principales: Schoeppe, Robert, Babl, Nathalie, Decking, Sonja-Maria, Schönhammer, Gabriele, Siegmund, Andreas, Bruss, Christina, Dettmer, Katja, Oefner, Peter J., Frick, Linus, Weigert, Anna, Jantsch, Jonathan, Herr, Wolfgang, Rehli, Michael, Renner, Kathrin, Kreutz, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894315/
https://www.ncbi.nlm.nih.gov/pubmed/36741028
http://dx.doi.org/10.3389/fonc.2023.1120194