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Robust performance of a live bacterial therapeutic chassis lacking the colibactin gene cluster
E. coli Nissle (EcN) is a non-pathogenic probiotic bacterium of the Enterobacteriaceae family that has been used for over a century to promote general gut health. Despite the history of safe usage of EcN, concerns have been raised regarding the presence of the pks gene cluster, encoding the genotoxi...
Autores principales: | Kalantari, Aida, James, Michael J., Renaud, Lauren A., Perreault, Mylene, Monahan, Catherine E., McDonald, Mary N., Hava, David L., Isabella, Vincent M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894410/ https://www.ncbi.nlm.nih.gov/pubmed/36730255 http://dx.doi.org/10.1371/journal.pone.0280499 |
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