Robust performance of a live bacterial therapeutic chassis lacking the colibactin gene cluster

E. coli Nissle (EcN) is a non-pathogenic probiotic bacterium of the Enterobacteriaceae family that has been used for over a century to promote general gut health. Despite the history of safe usage of EcN, concerns have been raised regarding the presence of the pks gene cluster, encoding the genotoxi...

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Detalles Bibliográficos
Autores principales: Kalantari, Aida, James, Michael J., Renaud, Lauren A., Perreault, Mylene, Monahan, Catherine E., McDonald, Mary N., Hava, David L., Isabella, Vincent M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894410/
https://www.ncbi.nlm.nih.gov/pubmed/36730255
http://dx.doi.org/10.1371/journal.pone.0280499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894410/
https://www.ncbi.nlm.nih.gov/pubmed/36730255
http://dx.doi.org/10.1371/journal.pone.0280499

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