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Shape-specific characterization of colorectal adenoma growth and transition to cancer with stochastic cell-based models

Colorectal adenoma are precursor lesions on the pathway to cancer. Their removal in screening colonoscopies has markedly reduced rates of cancer incidence and death. Generic models of adenoma growth and transition to cancer can guide the implementation of screening strategies. But adenoma shape has...

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Detalles Bibliográficos
Autores principales: Simonetto, Cristoforo, Mansmann, Ulrich, Kaiser, Jan Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894544/
https://www.ncbi.nlm.nih.gov/pubmed/36689547
http://dx.doi.org/10.1371/journal.pcbi.1010831