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Latent CMV infection of Lymphatic endothelial cells is sufficient to drive CD8 T cell memory inflation

CMV, a ubiquitous herpesvirus, elicits an extraordinarily large T cell response that is sustained or increases over time, a phenomenon termed ‘memory inflation.’ Remarkably, even latent, non-productive infection can drive memory inflation. Despite intense research on this phenomenon, the infected ce...

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Detalles Bibliográficos
Autores principales: Munks, Michael W., Rott, Katherine, Nesterenko, Pavlo A., Smart, Savannah M., Williams, Venasha, Tatum, Angela, Xu, Guangwu, Smith, Tameka, Murray, Susan E., Hill, Ann B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894547/
https://www.ncbi.nlm.nih.gov/pubmed/36689486
http://dx.doi.org/10.1371/journal.ppat.1010351