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Decomposing heritability and genetic covariance by direct and indirect effect paths

Estimation of heritability and genetic covariance is crucial for quantifying and understanding complex trait genetic architecture and is employed in almost all recent genome-wide association studies (GWAS). However, many existing approaches for heritability estimation and almost all methods for esti...

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Detalles Bibliográficos
Autores principales: Song, Jie, Zou, Yiqing, Wu, Yuchang, Miao, Jiacheng, Yu, Ze, Fletcher, Jason M., Lu, Qiongshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894552/
https://www.ncbi.nlm.nih.gov/pubmed/36689559
http://dx.doi.org/10.1371/journal.pgen.1010620