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Yeast derlin Dfm1 employs a chaperone-like function to resolve misfolded membrane protein stress

Protein aggregates are a common feature of diseased and aged cells. Membrane proteins comprise a quarter of the proteome, and yet, it is not well understood how aggregation of membrane proteins is regulated and what effects these aggregates can have on cellular health. We have determined in yeast th...

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Detalles Bibliográficos
Autores principales: Kandel, Rachel, Jung, Jasmine, Syau, Della, Kuo, Tiffany, Songster, Livia, Horn, Casey, Chapman, Claire, Aguayo, Analine, Duttke, Sascha, Benner, Christopher, Neal, Sonya E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894555/
https://www.ncbi.nlm.nih.gov/pubmed/36689475
http://dx.doi.org/10.1371/journal.pbio.3001950