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Yeast derlin Dfm1 employs a chaperone-like function to resolve misfolded membrane protein stress
Protein aggregates are a common feature of diseased and aged cells. Membrane proteins comprise a quarter of the proteome, and yet, it is not well understood how aggregation of membrane proteins is regulated and what effects these aggregates can have on cellular health. We have determined in yeast th...
Autores principales: | Kandel, Rachel, Jung, Jasmine, Syau, Della, Kuo, Tiffany, Songster, Livia, Horn, Casey, Chapman, Claire, Aguayo, Analine, Duttke, Sascha, Benner, Christopher, Neal, Sonya E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894555/ https://www.ncbi.nlm.nih.gov/pubmed/36689475 http://dx.doi.org/10.1371/journal.pbio.3001950 |
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