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Follicular Lymphoma Microenvironment Characteristics Associated with Tumor Cell Mutations and MHC Class II Expression

Follicular lymphoma (FL) is a B-cell malignancy with a complex tumor microenvironment that is rich in nonmalignant immune cells. We applied single-cell RNA sequencing to characterize the diverse tumor and immune cell populations of FL and identified major phenotypic subsets of FL T cells, including...

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Detalles Bibliográficos
Autores principales: Han, Guangchun, Deng, Qing, Marques-Piubelli, Mario L., Dai, Enyu, Dang, Minghao, Ma, Man Chun John, Li, Xubin, Yang, Haopeng, Henderson, Jared, Kudryashova, Olga, Meerson, Mark, Isaev, Sergey, Kotlov, Nikita, Nomie, Krystle J., Bagaev, Alexander, Parra, Edwin R., Solis Soto, Luisa M., Parmar, Simrit, Hagemeister, Fredrick B., Ahmed, Sairah, Iyer, Swaminathan P., Samaniego, Felipe, Steiner, Raphael, Fayad, Luis, Lee, Hun, Fowler, Nathan H., Flowers, Christopher R., Strati, Paolo, Westin, Jason R., Neelapu, Sattva S., Nastoupil, Loretta J., Vega, Francisco, Wang, Linghua, Green, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894575/
https://www.ncbi.nlm.nih.gov/pubmed/35687817
http://dx.doi.org/10.1158/2643-3230.BCD-21-0075