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Deep Morphology Learning Enhances Ex Vivo Drug Profiling-Based Precision Medicine

Drug testing in patient biopsy-derived cells can identify potent treatments for patients suffering from relapsed or refractory hematologic cancers. Here we investigate the use of weakly supervised deep learning on cell morphologies (DML) to complement diagnostic marker-based identification of malign...

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Detalles Bibliográficos
Autores principales: Heinemann, Tim, Kornauth, Christoph, Severin, Yannik, Vladimer, Gregory I., Pemovska, Tea, Hadzijusufovic, Emir, Agis, Hermine, Krauth, Maria-Theresa, Sperr, Wolfgang R., Valent, Peter, Jäger, Ulrich, Simonitsch-Klupp, Ingrid, Superti-Furga, Giulio, Staber, Philipp B., Snijder, Berend
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894727/
https://www.ncbi.nlm.nih.gov/pubmed/36125297
http://dx.doi.org/10.1158/2643-3230.BCD-21-0219