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Deep Morphology Learning Enhances Ex Vivo Drug Profiling-Based Precision Medicine
Drug testing in patient biopsy-derived cells can identify potent treatments for patients suffering from relapsed or refractory hematologic cancers. Here we investigate the use of weakly supervised deep learning on cell morphologies (DML) to complement diagnostic marker-based identification of malign...
Autores principales: | Heinemann, Tim, Kornauth, Christoph, Severin, Yannik, Vladimer, Gregory I., Pemovska, Tea, Hadzijusufovic, Emir, Agis, Hermine, Krauth, Maria-Theresa, Sperr, Wolfgang R., Valent, Peter, Jäger, Ulrich, Simonitsch-Klupp, Ingrid, Superti-Furga, Giulio, Staber, Philipp B., Snijder, Berend |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894727/ https://www.ncbi.nlm.nih.gov/pubmed/36125297 http://dx.doi.org/10.1158/2643-3230.BCD-21-0219 |
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