Sample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression

Targeted proteomics enables hypothesis-driven research by measuring the cellular expression of protein cohorts related by function, disease, or class after perturbation. Here, we present a pathway-centric approach and an assay builder resource for targeting entire pathways of up to 200 proteins sele...

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Detalles Bibliográficos
Autores principales: Yu, Qing, Liu, Xinyue, Keller, Mark P., Navarrete-Perea, Jose, Zhang, Tian, Fu, Sipei, Vaites, Laura P., Shuken, Steven R., Schmid, Ernst, Keele, Gregory R., Li, Jiaming, Huttlin, Edward L., Rashan, Edrees H., Simcox, Judith, Churchill, Gary A., Schweppe, Devin K., Attie, Alan D., Paulo, Joao A., Gygi, Steven P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894840/
https://www.ncbi.nlm.nih.gov/pubmed/36732331
http://dx.doi.org/10.1038/s41467-023-36269-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894840/
https://www.ncbi.nlm.nih.gov/pubmed/36732331
http://dx.doi.org/10.1038/s41467-023-36269-7

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