Sal003 alleviated intervertebral disc degeneration by inhibiting apoptosis and extracellular matrix degradation through suppressing endoplasmic reticulum stress pathway in rats

Apoptosis and extracellular matrix degradation of the nucleus pulposus are the main initiators of intervertebral disc degeneration (IVDD) and can be explained by endoplasmic reticulum (ER) stress. Thus, pharmacological therapy aimed at suppressing this pathway may be a promising approach for the man...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Li, Baixing, Xu, Yue, Zhou, Tangjun, Zhao, Changqing, Zhao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894885/
https://www.ncbi.nlm.nih.gov/pubmed/36744257
http://dx.doi.org/10.3389/fphar.2023.1095307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894885/
https://www.ncbi.nlm.nih.gov/pubmed/36744257
http://dx.doi.org/10.3389/fphar.2023.1095307

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