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Distinct spatiotemporal subtypes of amyloid deposition are associated with diverging disease profiles in cognitively normal and mild cognitive impairment individuals

We aimed to investigate the relationship between spatiotemporal changes of amyloid deposition and Alzheimer’s disease (AD) profiles in cognitively normal (CN) and those with mild cognitive impairment (MCI). Using a data-driven method and amyloid-PET data, we identified and validated two subtypes in...

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Detalles Bibliográficos
Autores principales: Sun, Yuqing, Zhao, Yuxin, Hu, Ke, Wang, Meng, Liu, Yong, Liu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895066/
https://www.ncbi.nlm.nih.gov/pubmed/36732496
http://dx.doi.org/10.1038/s41398-023-02328-2