Scale down and optimized automated production of [68Ga]68Ga-DOTA-ECL1i PET tracer targeting CCR2 expression

BACKGROUND: Recently it has been identified a short peptide that showed allosteric antagonism against C–C motif chemokine receptor 2 (CCR2) expressed on inflammatory monocyte and macrophages. A 7-d-amino acid peptidic CCR2 inhibitor called extracellular loop 1 inverso (ECL1i), d(LGTFLKC) has been id...

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Detalles Bibliográficos
Autores principales: Migliari, Silvia, Scarlattei, Maura, Baldari, Giorgio, Ruffini, Livia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895323/
https://www.ncbi.nlm.nih.gov/pubmed/36729317
http://dx.doi.org/10.1186/s41181-023-00188-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895323/
https://www.ncbi.nlm.nih.gov/pubmed/36729317
http://dx.doi.org/10.1186/s41181-023-00188-1

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