Nanomolar clodronate induces adenosine accumulation in the perfused rat mesenteric bed and mesentery-derived endothelial cells

The vesicular nucleotide transporter (VNUT) is critical for sympathetic co-transmission and purinergic transmission maintenance. To examine this proposal, we assessed whether the bisphosphonate clodronate, claimed as a potent in vitro VNUT blocker, modified spontaneous and/or the electrically evoked...

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Detalles Bibliográficos
Autores principales: Donoso, M. Verónica, Hernández, Felipe, Barra, Rafael, Huidobro-Toro, J. Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895365/
https://www.ncbi.nlm.nih.gov/pubmed/36744214
http://dx.doi.org/10.3389/fphar.2022.1031223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895365/
https://www.ncbi.nlm.nih.gov/pubmed/36744214
http://dx.doi.org/10.3389/fphar.2022.1031223

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