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Downregulation of ITGβ3 in colon adenocarcinoma reveals poor prognosis by affecting genome stability, cell cycle, and the tumor immune microenvironment

INTRODUCTION: Abnormal expression of integrin subunit beta 3 (ITGβ3), a gene-encoding protein, is related to the occurrence and development of cancers; however, the biological role of ITGβ3 in colon adenocarcinoma (COAD) remains unclear. METHODS: We used the Cancer Genome Atlas database to obtain th...

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Detalles Bibliográficos
Autores principales: Zhao, Lei, Ma, Xiaoting, Li, Guangxin, Zhao, Pengfei, Lin, Haishan, Ma, Yingjie, Li, Huihui, Yu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895777/
https://www.ncbi.nlm.nih.gov/pubmed/36741730
http://dx.doi.org/10.3389/fonc.2022.1047648