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Genetic removal of synaptic Zn(2+) impairs cognition, alters neurotrophic signaling and induces neuronal hyperactivity
Vesicular Zn(2+) (zinc) is released at synapses and has been demonstrated to modulate neuronal responses. However, mechanisms through which dysregulation of zinc homeostasis may potentiate neuronal dysfunction and neurodegeneration are not well-understood. We previously reported that accumulation of...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895830/ https://www.ncbi.nlm.nih.gov/pubmed/36742045 http://dx.doi.org/10.3389/fneur.2022.882635 |