Folate-deficiency induced acyl-CoA synthetase short-chain family member 2 increases lysine crotonylome involved in neural tube defects

Maternal folate deficiency increases the risk of neural tube defects (NTDs), but the mechanism remains unclear. Here, we established a mouse model of NTDs via low folate diets combined with MTX-induced conditions. We found that a significant increase in butyrate acid was observed in mouse NTDs brain...

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Detalles Bibliográficos
Autores principales: Wang, Shan, Zeng, Yubing, He, Xuejia, Liu, Fan, Pei, Pei, Zhang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895841/
https://www.ncbi.nlm.nih.gov/pubmed/36743291
http://dx.doi.org/10.3389/fnmol.2022.1064509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895841/
https://www.ncbi.nlm.nih.gov/pubmed/36743291
http://dx.doi.org/10.3389/fnmol.2022.1064509

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