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Targeting influenza A virus by splicing inhibitor herboxidiene reveals the importance of subtype-specific signatures around splice sites

BACKGROUND: The association between M segment splicing and pathogenicity remains ambiguous in human influenza A viruses. In this study, we aimed to investigate M splicing in various human influenza A viruses and characterize its physiological roles by applying the splicing inhibitor, herboxidiene. M...

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Detalles Bibliográficos
Autores principales: Han, Yi-Ju, Lee, Kuo-Ming, Wu, Guan-Hong, Gong, Yu-Nong, Dutta, Avijit, Shih, Shin-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895974/
https://www.ncbi.nlm.nih.gov/pubmed/36737756
http://dx.doi.org/10.1186/s12929-023-00897-4