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Targeting influenza A virus by splicing inhibitor herboxidiene reveals the importance of subtype-specific signatures around splice sites
BACKGROUND: The association between M segment splicing and pathogenicity remains ambiguous in human influenza A viruses. In this study, we aimed to investigate M splicing in various human influenza A viruses and characterize its physiological roles by applying the splicing inhibitor, herboxidiene. M...
Autores principales: | Han, Yi-Ju, Lee, Kuo-Ming, Wu, Guan-Hong, Gong, Yu-Nong, Dutta, Avijit, Shih, Shin-Ru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895974/ https://www.ncbi.nlm.nih.gov/pubmed/36737756 http://dx.doi.org/10.1186/s12929-023-00897-4 |
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