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Discovery of a novel, liver-targeted thyroid hormone receptor-β agonist, CS271011, in the treatment of lipid metabolism disorders

INTRODUCTION: Thyroid hormone receptor β (THR-β) plays a critical role in metabolism regulation and has become an attractive target for treating lipid metabolism disorders in recent years. Thus, in this study, we discovered CS271011, a novel THR-β agonist, and assessed the safety and efficiency of C...

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Detalles Bibliográficos
Autores principales: Lin, Suwen, Huang, Shengjian, Deng, Zhou, Zhang, Yu, Huang, Lin, Wu, Yanyi, Lv, Shuyan, Wang, Zhiyi, Huang, Ning, Wang, Lan, Chen, Ziqi, Yu, Guangyin, Yin, Weihua, Zhou, You, Fang, Zhengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896003/
https://www.ncbi.nlm.nih.gov/pubmed/36742393
http://dx.doi.org/10.3389/fendo.2023.1109615