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The adjuvants dmLT and mmCT enhance humoral immune responses to a pneumococcal conjugate vaccine after both parenteral or mucosal immunization of neonatal mice

Immaturity of the neonatal immune system contributes to increased susceptibility to infectious diseases and poor vaccine responses. Therefore, better strategies for early life vaccination are needed. Adjuvants can enhance the magnitude and duration of immune responses. In this study we assessed the...

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Detalles Bibliográficos
Autores principales: Molina Estupiñan, Jenny Lorena, Aradottir Pind, Audur Anna, Foroutan Pajoohian, Poorya, Jonsdottir, Ingileif, Bjarnarson, Stefania P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896006/
https://www.ncbi.nlm.nih.gov/pubmed/36741402
http://dx.doi.org/10.3389/fimmu.2022.1078904