Pharmacological Targeting of Androgen Receptor Elicits Context-Specific Effects in Estrogen Receptor–Positive Breast Cancer

Androgen receptor (AR) is expressed in 80% to 90% of estrogen receptor α–positive (ER(+)) breast cancers. Accumulated evidence has shown that AR is a tumor suppressor and that its expression is associated with improved prognosis in ER(+) breast cancer. However, both a selective AR agonist (RAD140) a...

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Detalles Bibliográficos
Autores principales: Wei, Lixuan, Gao, Huanyao, Yu, Jia, Zhang, Huan, Nguyen, Thanh Thanh L., Gu, Yayun, Passow, Marie R., Carter, Jodi M., Qin, Bo, Boughey, Judy C., Goetz, Matthew P., Weinshilboum, Richard M., Ingle, James N., Wang, Liewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Translational Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896025/
https://www.ncbi.nlm.nih.gov/pubmed/36469363
http://dx.doi.org/10.1158/0008-5472.CAN-22-1016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896025/
https://www.ncbi.nlm.nih.gov/pubmed/36469363
http://dx.doi.org/10.1158/0008-5472.CAN-22-1016

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