Antigen-Loaded Extracellular Vesicles Induce Responsiveness to Anti–PD-1 and Anti–PD-L1 Treatment in a Checkpoint Refractory Melanoma Model

Extracellular vesicles (EV) are important mediators of intercellular communication and are potential candidates for cancer immunotherapy. Immune checkpoint blockade, specifically targeting the programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) axis, mitigates T-cell exhaustion,...

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Detalles Bibliográficos
Autores principales: Veerman, Rosanne E., Akpinar, Gözde Güclüler, Offens, Annemarijn, Steiner, Loïc, Larssen, Pia, Lundqvist, Andreas, Karlsson, Mikael C.I., Gabrielsson, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896027/
https://www.ncbi.nlm.nih.gov/pubmed/36546872
http://dx.doi.org/10.1158/2326-6066.CIR-22-0540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896027/
https://www.ncbi.nlm.nih.gov/pubmed/36546872
http://dx.doi.org/10.1158/2326-6066.CIR-22-0540

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