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Single‐Cell and Spatial Transcriptomics Decodes Wharton's Jelly‐Derived Mesenchymal Stem Cells Heterogeneity and a Subpopulation with Wound Repair Signatures

The highly heterogeneous characteristics of Wharton's jelly mesenchymal stem cells (WJ‐MSCs) may be responsible for the poor clinical outcomes and poor reproducibility of treatments based on WJ‐MSCs. Exploration of WJ‐MSC heterogeneity with multimodal single‐cell technologies will aid in establ...

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Detalles Bibliográficos
Autores principales: Chen, Penghong, Tang, Shijie, Li, Ming, Wang, Dezhi, Chen, Caixiang, Qiu, Yiqun, Fang, Zhuoqun, Zhang, Haoruo, Gao, Hangqi, Weng, Haiyan, Hu, Kailun, Lin, Jian, Lin, Qingxia, Tan, Yi, Li, Shirong, Chen, Jinghua, Chen, Liangwan, Chen, Xiaosong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896049/
https://www.ncbi.nlm.nih.gov/pubmed/36504438
http://dx.doi.org/10.1002/advs.202204786