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Insights into the Effect of Catalytic Intratumoral Lactate Depletion on Metabolic Reprogramming and Immune Activation for Antitumoral Activity

Lactate, a characteristic metabolite of the tumor microenvironment (TME), drives immunosuppression and promotes tumor progression. Material‐engineered strategies for intratumoral lactate modulations demonstrate their promise for tumor immunotherapy. However, understanding of the inherent interconnec...

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Detalles Bibliográficos
Autores principales: Zhao, Junlong, Tian, Zhimin, Zhao, Shoujie, Feng, Dayun, Guo, Zhixiong, Wen, Liangzhi, Zhu, Yejing, Xu, Fenghua, Zhu, Jun, Ma, Shouzheng, Hu, Jie, Jiang, Tao, Qu, Yongquan, Chen, Dongfeng, Liu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896070/
https://www.ncbi.nlm.nih.gov/pubmed/36479819
http://dx.doi.org/10.1002/advs.202204808