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Tropomyosin receptor kinase B (TrkB) signalling: targeted therapy in neurogenic tumours

Tropomyosin receptor kinase B (TrkB), a transmembrane receptor protein, has been found to play a pivotal role in neural development. This protein is encoded by the neurotrophic receptor tyrosine kinase 2 (NTRK2) gene, and its abnormal activation caused by NTRK2 overexpression or fusion can contribut...

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Detalles Bibliográficos
Autores principales: Li, Yuehua, Wei, Chengjiang, Wang, Wei, Li, Qingfeng, Wang, Zhi‐Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896160/
https://www.ncbi.nlm.nih.gov/pubmed/36533776
http://dx.doi.org/10.1002/cjp2.307