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Silencing of circ_002136 sensitizes gastric cancer to paclitaxel by targeting the miR-16-5p/HMGA1 axis

The dysregulated expression of circRNA in gastric cancer (GC) induces paclitaxel (Tax) resistance of cancer cells, which in turn affects disease progression and prognosis. Here, we sought to investigate the role and mechanism of circ_002136 in Tax-resistant GC. In this study, we found the enriched c...

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Detalles Bibliográficos
Autores principales: Kuang, Zhijian, Yang, Haitao, Cheng, Shu, Zhou, Xiaolong, Chen, Lan, Zhang, Yuqing, Zhang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896165/
https://www.ncbi.nlm.nih.gov/pubmed/36760722
http://dx.doi.org/10.1515/med-2022-0625