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High levels of kappa free light chain synthesis predict cognitive decline in relapsing-remitting multiple sclerosis

BACKGROUND: Evolving evidence suggests that measurement of cerebrospinal fluid (CSF) kappa free light chain (KFLC) synthesis has high diagnostic sensitivity and specificity for multiple sclerosis (MS), but its prognostic ability is less investigated. The usefulness of KFLC in predicting cognitive im...

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Detalles Bibliográficos
Autores principales: Rosenstein, Igal, Axelsson, Markus, Novakova, Lenka, Rasch, Sofia, Blennow, Kaj, Zetterberg, Henrik, Lycke, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896185/
https://www.ncbi.nlm.nih.gov/pubmed/36742305
http://dx.doi.org/10.3389/fimmu.2023.1106028