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Recurrent disability progression endpoints in multiple sclerosis clinical trials

BACKGROUND: The current standard endpoint to assess disability accumulation in multiple sclerosis (MS) clinical trials is the time to the first confirmed disability progression, which excludes subsequent progression events. Including recurrent progression events may permit a more comprehensive asses...

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Detalles Bibliográficos
Autores principales: Bühler, Alexandra, Wolbers, Marcel, Model, Fabian, Wang, Qing, Belachew, Shibeshih, Manfrini, Marianna, Lorscheider, Johannes, Kappos, Ludwig, Beyersmann, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896250/
https://www.ncbi.nlm.nih.gov/pubmed/36177953
http://dx.doi.org/10.1177/13524585221125382