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The population-wise error rate for clinical trials with overlapping populations

We introduce a new multiple type I error criterion for clinical trials with multiple, overlapping populations. Such trials are of interest in precision medicine where the goal is to develop treatments that are targeted to specific sub-populations defined by genetic and/or clinical biomarkers. The ne...

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Detalles Bibliográficos
Autores principales: Brannath, Werner, Hillner, Charlie, Rohmeyer, Kornelius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896298/
https://www.ncbi.nlm.nih.gov/pubmed/36453057
http://dx.doi.org/10.1177/09622802221135249