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Site-specific decreases in DNA methylation in replicating cells following exposure to oxidative stress

Oxidative stress is a common feature of inflammation-driven cancers, and it promotes genomic instability and aggressive tumour phenotypes. It is known that oxidative stress transiently modulates gene expression through the oxidation of transcription factors and associated regulatory proteins. Neutro...

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Detalles Bibliográficos
Autores principales: Seddon, Annika R, Das, Andrew B, Hampton, Mark B, Stevens, Aaron J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896486/
https://www.ncbi.nlm.nih.gov/pubmed/36106794
http://dx.doi.org/10.1093/hmg/ddac232