Alpha-synuclein oligomers alter the spontaneous firing discharge of cultured midbrain neurons

The aim of this work was to monitor the effects of extracellular α-synuclein on the firing activity of midbrain neurons dissociated from substantia nigra TH-GFP mice embryos and cultured on microelectrode arrays (MEA). We monitored the spontaneous firing discharge of the network for 21 days after pl...

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Detalles Bibliográficos
Autores principales: Tomagra, Giulia, Franchino, Claudio, Cesano, Federico, Chiarion, Giovanni, de lure, Antonio, Carbone, Emilio, Calabresi, Paolo, Mesin, Luca, Picconi, Barbara, Marcantoni, Andrea, Carabelli, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896582/
https://www.ncbi.nlm.nih.gov/pubmed/36744002
http://dx.doi.org/10.3389/fncel.2023.1078550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896582/
https://www.ncbi.nlm.nih.gov/pubmed/36744002
http://dx.doi.org/10.3389/fncel.2023.1078550

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